CALL FOR PAPERS Translational Research in Acute Lung Injury and Pulmonary Fibrosis Exposure to mechanical ventilation promotes tolerance to ventilator-induced lung injury by Ccl3 downregulation
نویسندگان
چکیده
Jorge Blázquez-Prieto, Inés López-Alonso, Laura Amado-Rodríguez, Estefanía Batalla-Solís, Adrián González-López, and Guillermo M. Albaiceta Departamento de Biología Funcional, Instituto Universitario de Oncología del Principado de Asturias, Universidad de Oviedo, Oviedo, Spain; Área de Gestión Clínica de Medicina Intensiva, Hospital Valle del Nalón, Langreo, Spain; Department of Anesthesiology and Operative Intensive Care Medicine, Charité Universitätsmedizin, Berlin, Germany; and Servicio de Medicina Intensiva, Hospital Universitario Central de Asturias, Oviedo, Spain
منابع مشابه
Exposure to mechanical ventilation promotes tolerance to ventilator-induced lung injury by Ccl3 downregulation.
Inflammation plays a key role in the development of ventilator-induced lung injury (VILI). Preconditioning with a previous exposure can damp the subsequent inflammatory response. Our objectives were to demonstrate that tolerance to VILI can be induced by previous low-pressure ventilation, and to identify the molecular mechanisms responsible for this phenomenon. Intact 8- to 12-wk-old male CD1 m...
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